Inside Front Cover: Rapid isolation and quantification of extracellular vesicles from suspension‐adapted human embryonic kidney cells using capillary‐channeled polymer fiber spin‐down tips

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چکیده

DOI: 10.1002/elps.202200149 The cover picture shows how capillary-channeled polymer (C-CP) fibers are applied in a spin-down tip format to isolate pure, concentrated populations of exosomes and other extracellular vesicles (EVs) from human embryonic kidney (HEK) cell culture media. Exosomes/EVs vehicles intercellular communication, containing genetic protein contents the mother cell. Beyond being fundamental biological interest having promise clinical diagnostics, exosomes/EVs evolving as key biotherapeutic delivery vectors, with HEK cells promising primary source. Successes here on analytical scale portend future use C-CP preparative towards vector production.

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ژورنال

عنوان ژورنال: Electrophoresis

سال: 2023

ISSN: ['0173-0835', '1522-2683']

DOI: https://doi.org/10.1002/elps.202370017